Cart
sales@molnova.com
Dexrazoxane hydrochloride
CAS No. 149003-01-0
Dexrazoxane hydrochloride( ICRF-187 hydrochloride )
Catalog No. M12061 CAS No. 149003-01-0
A derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 41 | In Stock |
|
| 25MG | 64 | In Stock |
|
| 50MG | 83 | In Stock |
|
| 100MG | 109 | In Stock |
|
| 200MG | 169 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDexrazoxane hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionA derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.
-
DescriptionA derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals; protects the heart against the cardiotoxic side effects of chemotherapeutic drugs.Chemotherapeutic Agents Approved.
-
In Vitro——
-
In Vivo——
-
SynonymsICRF-187 hydrochloride
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research AreaCancer
-
IndicationChemotherapeutic
Chemical Information
-
CAS Number149003-01-0
-
Formula Weight304.7301
-
Molecular FormulaC11H17ClN4O4
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(CN(C[C@@H](N1CC(NC(C1)=O)=O)C)C2)NC2=O.[H]Cl
-
Chemical Name1,3-Piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-, hydrochloride (1:?)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lipshultz SE, et al. N Engl J Med. 2004 Jul 8;351(2):145-53.
2. Bjelogrlic SK, et al. Exp Biol Med (Maywood). 2007 Dec;232(11):1414-24.
3. Jones RL, et al. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.
molnova catalog
related products
-
Methyl phenylacetate
Methyl phenylacetate (Methyl 2-phenylacetate) is a RIFM flavor extracted from the outer layer of fermenting mycelium.
-
Cyclo(Ile-Val)
Cyclo(Ile-Val) shows moderate antifungal and weak antitumor activities in vitro.
-
PCLX-001
PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively.
